By Gerhard F. Weinbauer,Friedhelm Vogel

ISBN-10: 3830928394

ISBN-13: 9783830928393

In continuation of the Covance Primate Symposium sequence, the nineteenth Covance Primate Symposium happened in Münster on twenty third & twenty fourth of could 2012. Altogether, 70 individuals representing forty three businesses, collected for this symposium.
The 2012 Primate Symposium focussed on ?Challenges in Nonhuman Primate study within the twenty first Century?. The large participation and the energetic discussions through the symposium underlined the timeliness and significance of this subject. specialist audio system lined 4 significant issues, i.e. biosimilars improvement: regulatory implications, key issues and subsequent steps, optimizing nonhuman primate use in nonclinical protection evaluation, traits in nonhuman primate developmental & reproductive toxicology (DART) and juvenile toxicity review, and relevance and significance of nonhuman primate types in regulatory toxicology. the improvement of biosimilar has taken up velocity significantly and in the meantime should be thought of a major factor of capability drug improvement, but there are nonetheless a few uncertainties und guidance are less than improvement. With the elevated concentrate on biopharmaceuticals and the linked raise for utilizing nonhuman primates being the correct animal version, it grew to become essential to optimize using this animal version, e.g. refine learn designs and animals numbers yet nonetheless execute significant preclinical reports. it seems that major growth has been completed in that context. within the region of nonhuman primate DART and juvenile toxicity review, contemporary guide alterations had a big impression on species choice, and the experimental layout plus the timing of those reviews in the preclinical programmes. ultimately, given the expanding laws and justficiations of utilizing nonhuman primates as experimental types. it's paramount to appreciate the basic and fundamental function that nonhuman primates can play in drug security assessment and scientific drug development.

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Challenges in Nonhuman Primate Research in the 21st Century by Gerhard F. Weinbauer,Friedhelm Vogel

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