By P. Alexander,J. Gielen,A. C. Sartorelli

ISBN-10: 0080320309

ISBN-13: 9780080320304

ISBN-10: 1483175022

ISBN-13: 9781483175027

Bioreduction within the Activation of gear covers the court cases of the second one Biochemical Pharmacology Symposium. The publication offers papers that disguise the purposes of bioreduction in drug activation, in addition to its issues.
The textual content first provides fabrics approximately enzymology, reminiscent of review of enzyme platforms considering bioreduction of gear and in redox biking, and reductive function of glutathione within the redox biking of oxidizable medications. subsequent, the e-book covers papers on bacterial and parasites an infection, which come with aid by means of the intestine microflora of animals and human and relief of nitroimidazoles in vitro and DNA harm. the remainder articles take care of melanoma remedy, reminiscent of hypoxia-mediated nitro-heterocyclic medicinal drugs within the radio- and chemotherapy of melanoma, and the organic homes of lowered nitroheterocyclics and attainable underlying biochemical mechanisms.
The textual content may be of serious use to researchers and practitioners of medication, pharmacology, and biochemistry.

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Bioreduction in the Activation of Drugs: Proceedings of the Second Biochemical Pharmacology Symposium, Oxford, UK, 25-26 July 1985 by P. Alexander,J. Gielen,A. C. Sartorelli


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